
Until now, it was thought that fructose was most likely to cause such changes.ĭevelopment of fatty liver or diabetes more likely

Particularly surprising was that the sugar we most commonly consume, sucrose, boosted fat synthesis slightly more than the same amount of fructose. Nevertheless, the researchers observed that fructose has a negative effect: "The body's own fat production in the liver was twice as high in the fructose group as in the glucose group or the control group-and this was still the case more than twelve hours after the last meal or sugar consumption," says Gerber. Overall, the participants did not consume more calories than before the study, as the sugary drink increased satiety and they therefore reduced their calorie intake from other sources. The researchers then used tracers (labeled substances that can be traced as they move through the body) to analyze the effect of the sugary drinks on the lipid metabolism.įructose and sucrose double fat production beyond food intake The drinks contained either fructose, glucose or sucrose (table sugar which is a combination of fructose and glucose). Every day for a period of seven weeks, they consumed a drink sweetened with different types of sugar, while the control group did not. Ninety-four healthy young men took part in the study. And the overactive fat production continues for a longer period of time, even if no more sugar is consumed," says study leader Philipp Gerber of the Department of Endocrinology, Diabetology and Clinical Nutrition. "Eighty grams of sugar daily, which is equivalent to about 0,8 liters of a normal soft drink, boosts fat production in the liver. Compared to previous studies, which mainly examined the consumption of very high amounts of sugar, their results show that even moderate amounts lead to a change in the metabolism of test participants.

Researchers at the University of Zurich (UZH) and the University Hospital Zurich (USZ) have been investigating these questions. But does too much sugar have any other harmful effects if consumed regularly? And if so, which sugars in particular?Įven moderate amounts of sugar increase fat synthesis The high calorie content of sugar causes excessive weight and obesity, and the associated diseases. What Should I Eat?.Sugar is added to many common foodstuffs, and people in Switzerland consume more than 100 grams of it every day. High Intake of Sugar and the Balance between Pro- and Anti-Inflammatory Gut Bacteria. Dietary pattern and depressive symptoms in middle age. The Dose Makes the Poison: Sugar and Obesity in the United States - a Review. 2020 31(2):233-249.e4.įaruque S, Tong J, Lacmanovic V, Agbonghae C, Minaya DM, Czaja K. Hepatic lipoprotein export and remission of human type 2 diabetes after weight loss. Preventing type 2 diabetes.Īl-Mrabeh A, Zhyzhneuskaya SV, Peters C, et al. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG) 2006.

Effect of diet on type 2 diabetes mellitus: A review. Harvard Health Publishing Harvard Medical School. Nutritional Psychiatry: Your Brain on Food. Sugar intake from sweet food and beverages, common mental disorder and depression: prospective findings from the Whitehall II study. Knüppel A, Shipley MJ, Llewellyn CH, Brunner EJ. A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning. Molteni R, Barnard RJ, Ying Z, Roberts CK, Gómez-Pinilla F. A high-fat high-sugar diet-induced impairment in place-recognition memory is reversible and training-dependent. Sugar and cardiovascular disease: a statement for healthcare professionals from the committee on nutrition of the council on nutrition, physical activity, and metabolism of the american heart association. Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults. Yang Q, Zhang Z, Gregg EW, Flanders WD, Merritt R, Hu FB. United States Department of Agriculture.Īmerican Heart Association.

Treasure Island (FL): StatPearls Publishing.ĭietary Guidelines for Americans, Ninth Edition. National Center for Biotechnology Information.
